The prostate is an exocrine gland of the male mammalian reproductive system. The primary function of its is to store as well as secrete a clear fluid that constitutes a maximum of one third of the volume of semen. A healthy human prostate is somewhat bigger than a walnut. It surrounds the urethra right below the urinary bladder and may be felt during a rectal exam. The male urethra has 2 functions: in order to carry urine from the bladder throughout urination and also to carry semen during ejaculation. The prostate additionally contains some smooth muscle which really helps to expel semen during ejaculation. In order to run efficiently, the prostate requires androgen – male hormones which are liable for male sex characteristics. The main man hormone is testosterone, which is created mainly by the testicles. A few male hormones are made in quantities that are small by the adrenal glands.
The prostate gland has 4 distinct glandular regions, two of which arise from different portions of the prostatic urethra:
1. The Peripheral Zone (PZ) – The sub-capsular portion of the posterior element of the prostate gland which in turn surrounds the distal urethra and also comprises up to seventy % of the standard prostate gland in men which are young. It is because of this percentage of the gland that greater than seventy % of prostatic cancers originate.
2. The Central Zone (CZ) – This zone constitutes around twenty five % of the normal prostate gland and surrounds the ejaculatory ducts. Central zone tumors account for over 25 % of all prostate cancers.
3. The Transition Zone (TZ) – This zone is responsible for five % of the prostate volume and hardly ever is linked with carcinoma. The transition zone surrounds the proximal urethra and may be the area of the prostate gland that develops throughout. It is involved in benign prostatic enlargement.
4. The Anterior Fibro-muscular zone – This zone accounts for about 5 % of the prostatic excess weight, is usually devoid of glandular elements, as well as composed just, as its name indicates, of fibrous tissue and muscle tissue.
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